TUSSIONEX | TUSSIONEX LEAN

Tussionex cough syrup contains a combination of chlorpheniramine and hydrocodone. Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Hydrocodone is a narcotic cough suppressant.

It is used to treat runny or stuffy nose, sneezing, and cough caused by the common cold or flu.

It may also be used for other purposes not listed here.

Important information

Tussionex cough syrup, Do not take Tussionex more often than prescribed. An overdose of Tussionex can cause life-threatening side effects. To be sure you get the correct dose, measure this medicine carefully with a marked measuring spoon or syringe, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Before you take this cough syrup, tell your doctor if you have asthma or another breathing disorder, a history of head injury or brain tumor, stomach or intestinal problems, liver or kidney disease, glaucoma, urination problems or an enlarged prostate, Addison’s disease, or underactive thyroid.

Tussionex cough  cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol while using this cough syrup. Alcohol may increase drowsiness and dizziness. Hydrocodone may be habit-forming and should be used only by the person it was prescribed for.

This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not give this medicine to a child younger than 6 years old.

Tussionex cough syrup contains a codeine derivative, which means that, along with stopping my cough, it usually gives me a warm and fuzzy feeling that wears off in a couple of hours or so.

This time, because I’d unwittingly (and stupidly) overdosed, the effect was very pronounced, and it was mixed with a sensation of nausea. I found it hard to sit up or stand up and went to bed, where I fell asleep immediately.

What Is Tussionex?

Tussionex is a prescription medication that includes a combination of chlorpheniramine—an antihistamine¹—and the opioid painkiller hydrocodone. It is prescribed to treat respiratory symptoms—such as coughs—related to allergies or colds.

Chlorpheniramine relieves allergies and prevents fluid buildup in the respiratory tract.² Hydrocodone is a narcotic medication that suppresses coughing and relieves pain. It belongs to a class of drugs known as opioids,² which includes serious drugs of abuse like heroin, as well as various prescription painkillers.

Hydrocodone can produce euphoria or feelings of well-being and lead to dependence if taken for an extended period of time.^1,2 If someone misuses or abuseslean, this can increase the likelihood of addiction and harmful effects.

TUSSIONEX Pennkinetic Extended-Release Suspension is indicated for relief of cough and
upper respiratory symptoms associated with allergy or a cold in adults and children 6 years of age
and older.
CONTRAINDICATIONS
TUSSIONEX Pennkinetic Extended-Release Suspension is contraindicated in patients with a
known allergy or sensitivity to hydrocodone or chlorpheniramine.
The use of TUSSIONEX Pennkinetic Extended-Release Suspension is contraindicated in children
less than 6 years of age due to the risk of fatal respiratory depression.
WARNINGS
Risk from Concomitant Use with Benzodiazepines or other CNS Depressants
Concomitant use of opioids, including Pennkinetic Extended-Release Suspension,
with benzodiazepines, or other CNS depressants, including alcohol, may result in profound
sedation, respiratory depression, coma, and death. Because of these risks, avoid use of opioid
cough medications in patients taking benzodiazepines, other CNS depressants, or alcohol (see
PRECAUTIONS – Drug Interactions).
Observational studies have demonstrated that concomitant use of opioid analgesics and
benzodiazepines increases the risk of drug-related mortality compared to use of opioids alone.
Because of similar pharmacologic properties, it is reasonable to expect similar risk with
concomitant use of opioid cough medications and benzodiazepines, other CNS depressants, or
alcohol.
Advise both patients and caregivers about the risks of respiratory depression and sedation if
Pennkinetic Extended-Release Suspension is used with benzodiazepines, alcohol,
or other CNS depressants (see PRECAUTIONS – Information for Patients).
Respiratory Depression
As with all narcotics, TUSSIONEX Pennkinetic Extended-Release Suspension produces doserelated respiratory depression by directly acting on brain stem respiratory centers. Hydrocodone
affects the center that controls respiratory rhythm and may produce irregular and periodic
breathing. Caution should be exercised when TUSSIONEX Pennkinetic Extended-Release
Suspension is used postoperatively and in patients with pulmonary disease, or whenever
ventilatory function is depressed. If respiratory depression occurs, it may be antagonized by the
use of naloxone hydrochloride and other supportive measures when indicated (see
OVERDOSAGE)

Tussionex is a brand name prescription medication, made as a combination of hydrocodone and chlorpheniramine. Tussionex is used to treat the symptoms of cough and runny nose when a prescription strength medication is needed.